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H9006
Sigma
7-(β-Hydroxyethyl)theophylline
solid
| Synonym: | 1,3-Dimethyl-7-(2-hydroxyethyl)xanthine |
| CAS Number: | 519-37-9 |
| Linear Formula: | C9H12N4O3 |
| Molecular Weight: | 224.22 |
| EC Number: | 208-269-8 |
| MDL number: | MFCD00055055 |
| PubChem Substance ID: | 24895836 |
Description
| Application | Useful synthetic intermediate in the preparation of 7-substituted xanthines. |
| Biochem/physiol Actions | Pharmacological profile similar to theophylline. |
Properties
| form | solid |
| color | white |
| solubility | H2O: Solutions may be stored for several days at 4°C.soluble |
| ethanol: Solutions may be stored for several days at 4°C. moderately soluble | |
| Gene Information | human ... ADORA2B(136) |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| WGK Germany | 3 |
| RTECS | XH5850000 |
References
| reference | Hashimoto, et al., Adenosine as an endogenous mediator of hypoxia for induction of vascular endothelial growth factor mRNA in U-937 cells. Biochem. Biophys. Res. Commun. 204, 318-324, (1994) Abstract |
| Daly, et al., Analogs of caffeine and theophylline: Effect of structural alterations on affinity at adenosine receptors. J. Med. Chem. 29, 1305, (1986) Abstract |






