H9006

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H9006

Sigma

 

7-(β-Hydroxyethyl)theophylline

solid

Synonym:1,3-Dimethyl-7-(2-hydroxyethyl)xanthine
CAS Number:519-37-9
Linear Formula:C9H12N4O3
Molecular Weight:224.22
EC Number:208-269-8
MDL number:MFCD00055055
PubChem Substance ID:24895836

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Description

ApplicationUseful synthetic intermediate in the preparation of 7-substituted xanthines.
Biochem/physiol ActionsPharmacological profile similar to theophylline.

Properties

formsolid
color white
solubilityH2O: Solutions may be stored for several days at 4°C.soluble
 ethanol: Solutions may be stored for several days at 4°C. moderately soluble
Gene Informationhuman ... ADORA2B(136)

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXn
Risk Statements22
Safety Statements36
WGK Germany3
RTECSXH5850000

References

referenceHashimoto, et al., Adenosine as an endogenous mediator of hypoxia for induction of vascular endothelial growth factor mRNA in U-937 cells. Biochem. Biophys. Res. Commun. 204, 318-324, (1994) Abstract
 Daly, et al., Analogs of caffeine and theophylline: Effect of structural alterations on affinity at adenosine receptors. J. Med. Chem. 29, 1305, (1986) Abstract